ZMB – Zentrum für Medizinische Biotechnology (Universität Duisburg-Essen)


The Centre for Medical Biotechnology (ZMB) is an interdisciplinary scientific centre of the University of Duisburg-Essen, integrating medical research at the University Hospital and natural sciences at the Campus.

The mission of the ZMB is to elucidate molecular mechanisms of disease and to turn this knowledge into medical progress. To this end the ZMB is active in key areas of basic biomedical research, and in the translation of scientific knowledge into novel drugs and diagnostic tools. Accordingly, the 55 workgroups of the ZMB combine basic and applied biomedical sciences. Research is structured into four interdisciplinary programmes with numerous links between these programmes.

A dynamic, stimulating and collaborative research environment includes state of the art facilities and more than 300 highly educated personnel. Our interdisciplinary research crosses traditional boundaries and involves joint projects with the biotechnical and pharmaceutical industry, nanotechnology, physics and engineering.

The ZMB hosts several educational programmes in biomedical research. The Bachelor- and Master Schemes in Medical Biology prepare for a scientific career in the biomedical field and graduates have a choice of various PhD programmes.


1. Oncology

The concept of this research programme is to understand fundamental processes in tumor biology in order to develop novel molecularly defined and rationally applied cancer treatments. Participating researchers from biology, experimental and clinical medicine study tumors as “biological systems“ and so called “neo-organs”. A large variety of approaches, experimental systems and methodologies are in place to analyse many aspects of tumor development, growth, progression and tumor cell migration.

2. Immunology, Infectious Diseases and Transplantation

The immune system responds to various pathogens including viruses and bacteria in different ways to prevent severe disease and persistence in the host. Many pathogens, however, have developed mechanisms to evade immune defence. The molecular and cellular interactions of pathogens with the immune system are studied within this programme.

3. Molecular and Chemical Cell Biology

Molecular and chemical cell biology is an interdisciplinary research programme connecting molecular cell biology and genetics with chemistry and structural biology. Scientists of the participating disciplines collaborate to advance the understanding of basic molecular mechanisms of important biological processes. The analysis of regulation and deregulation of key pathways is linking basic biology with pathophysiology.

Links – ZMB – Zentrum für Medizinische Biotechnologie (Universität Duisburg-Essen)